Applications

Bioprocess mAb Capture

• Bulk mAb capture and elution, without the need for expensive chromatography columns or resins.
• Rapid and robust. Works even in crude harvest cell culture supernatents.
• Simple process, easily scaled-up.
• Reduces process steps, equipment, reagents, and production time.

T-Cell Activation

• No magnetic nanoparticles required.
• Minimal cell manipulation necessary.
• Results in robust expansion and activation in culture.

Cell Selection

• Soluble reagents are filter-sterilizable and amenable to automation processes.
• Soluble magnetic nanoparticles can be washed away from selected cells easily.
• Sequential cell selections, using different stimuli and thresholds, are possible.

Diagnostics

• Increased sensitivity and speed.
• Amenable to automation.
• Stimuli-responsive polymers can be conjugated to nucleic acid, protein, or synthetic probes.
• Biomarkers such as HIV p24 antigens are captured more rapidly and efficiently than with Dynal magnetic microbeads.